BDBM35254 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine::CHEMBL715::Olansek::US8802672, Olanzapine::Zyprexa::olanzapine
SMILES CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12
InChI Key InChIKey=KVWDHTXUZHCGIO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 35254
Affinity DataKi: 20nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:In vitro binding affinity towards Dopamine receptor D3 in Sf9 cell membranes using [3H]7-OH-DPAT as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Half-maximal inhibition of [3H]-spiperone binding to Dopamine receptor D3 in rat tissue homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Binding affinity to dopamine D3 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Inhibition of [3H]-7-OH-DPAT binding to Dopamine D3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Displacement of [3H]7OH-DPAT from dopamine D3 receptor (unknown origin) expressed in Sf9 cells by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Displacement of [3H]nemonapride from Rattus norvegicus (rat) wild type dopamine D3 receptor transfected in african green monkey COS7 cells after 1 hr...More data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Inhibition of [125I]-iodosulpride binding to human Dopamine receptor D3More data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:Binding affinity to human cloned dopamine D3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:Displacement of [3H]nemonapride from Rattus norvegicus (rat) chimeric dopamine D3 trunk/D3 tail receptor transfected in african green monkey COS7 cel...More data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Binding affinity towards human dopamine receptor D3More data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Binding affinity towards human Dopamine receptor D3More data for this Ligand-Target Pair
Affinity DataKi: 76nMAssay Description:Binding assays were carried out on rat recombinant D3 receptors (Perkin-Elmer, Cat. No. 6110139) expressed in Sf9 cells using [3H]spiperone (0.44-1.4...More data for this Ligand-Target Pair